Antioxidant intake is associated with semen quality in healthy men. Eskenazi B, Kidd SA, Marks AR, Sloter E, Block G, Wyrobek AJ. 140 Earl Warren Hall, School of Public Health, University of California, Berkeley, CA 94720-7360, USA. eskenazi@berkeley.edu BACKGROUND: We seek to determine whether dietary and supplement intake of specific micronutrients (zinc and folate) and antioxidants (vitamins C, E and beta-carotene) is associated with semen quality. METHODS: Ninety-seven healthy, non-smoking m...

Correlation between seminal carnitine and functional spermatozoal characteristics in men with semen dysfunction of various origins. De Rosa M, Boggia B, Amalfi B, Zarrilli S, Vita A, Colao A, Lombardi G. Department of Molecular and Clinical Endocrinology and Oncology, University of Naples Federico II, Naples, Italy. miderosa@unina.it BACKGROUND AND OBJECTIVE: L-carnitine is an essential molecule involved in mitochondrial metabolism, controlling the transport of acetyl and acyl groups across the ...

Relationship between seminal ascorbic acid and sperm DNA integrity in infertile men. Song GJ, Norkus EP, Lewis V. Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY 14642, USA. Ascorbic acid has recently been reported to protect sperm DNA from the damage induced by exogenous oxidative stress in vitro. But, there is no report on seminal ascorbic acid and sperm DNA fragmentation in infertile men. In this study, we asked whether sperm DNA damage correlate...

Effect of seminal oxidative stress on fertility after vasectomy reversal. Kolettis PN, Sharma RK, Pasqualotto FF, Nelson D, Thomas AJ Jr, Agarwal A. Department of Urology, Cleveland Clinic Foundation, Ohio 44195, USA. OBJECTIVE: To evaluate seminal oxidative stress in men after vasectomy reversal and to determine whether seminal oxidative stress could predict fertility after vasectomy reversal. DESIGN: Measurement of seminal reactive oxygen species (ROS) and total antioxidant capacity (TAC) in n...

Effect of cigarette smoking on levels of seminal oxidative stress in infertile men: a prospective study. Saleh RA, Agarwal A, Sharma RK, Nelson DR, Thomas AJ Jr. Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Urological Institute, The Cleveland Clinic Foundation, Ohio 44195, USA. OBJECTIVE: To investigate levels of seminal oxidative stress (OS) and sperm quality in a group of infertile men with a history of cigarette smoking.DESIGN: A prospective clinical s...

Negative effects of increased sperm DNA damage in relation to seminal oxidative stress in men with idiopathic and male factor infertility. Saleh RA, Agarwal A, Nada EA, El-Tonsy MH, Sharma RK, Meyer A, Nelson DR, Thomas AJ. Center for Advanced Research in Human Reproduction, Infertility, and Sexual Function, Urological Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. OBJECTIVE: To examine the effects of increased sperm DNA damage in relation to seminal oxidative stress in ...

Coenzyme Q(10) supplementation in infertile men with idiopathic asthenozoospermia: an open, uncontrolled pilot study. Balercia G, Mosca F, Mantero F, Boscaro M, Mancini A, Ricciardo-Lamonica G, Littarru G. Department of Internal Medicine, Umberto I Hospital, School of Medicine, University of Ancona, Ancona, Italy. g.balercia@ao-umbertoprimo.marche.it OBJECTIVE: To clarify a potential therapeutic role of coenzyme Q(10) (CoQ(10)) in infertile men with idiopathic asthenozoospermia. DESIGN: Open, u...

An update of Coenzyme Q10 implications in male infertility: biochemical and therapeutic aspects. Mancini A, De Marinis L, Littarru GP, Balercia G. Operative Unit of Endocrinology, Catholic University School of Medicine, Rome, Italy. Mancini.giac@mclink.it This review is focused upon the role of coenzyme Q(10) in male infertility in the light of a broader issue of oxidative damage and antioxidant defence in sperm cells and seminal plasma. Reactive oxygen species play a key pathogenetic role in m...

[Biological function of CoQ10 and its effect on the quality of spermatozoa] [Article in Chinese] Li W, Li K, Huang YF. Institute of Clinical Laboratory Medicine, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China. Oxidative damage is one of the important factors inducing the regression of sperm quality. CoQ10 is a liposoluble antioxidant that exists in mitochondria and its levels in semen and spermatozoa have an important role in the oxidation resistance of the male...

A scientific review: the role of chromium in insulin resistance. [No authors listed] Chromium is an essential mineral that appears to have a beneficial role in the regulation of insulin action and its effects on carbohydrate, protein and lipid metabolism. Chromium is an important factor for enhancing insulin activity. Studies show that people with type 2 diabetes have lower blood levels of chromium than those without the disease. Insulin resistance is the common denominator in a cluster of cardi...