Chromium picolinate improves insulin sensitivity in obese subjects with polycystic ovary syndrome.

Lydic ML, McNurlan M, Bembo S, Mitchell L, Komaroff E, Gelato M.

Department of Obstetrics, Gynecology, and Reproductive Medicine, Division of Reproductive Endocrinology, Stony Brook University Hospital, State University of New York-Stony Brook School of Medicine, 1794-8091, USA. mlydic@notes2.cc.sunysb.edu

Trivalent chromium (1000 microg), as chromium picolinate, given without change in diet or activity level, caused a 38% mean improvement in glucose disposal rate in five obese subjects with polycystic ovary syndrome who were tested with a euglycemic hyperinsulinemic clamp technique. This suggests that chromium picolinate, an over-the-counter dietary product, may be useful as an insulin sensitizer in the treatment of polycystic ovary syndrome.

PMID: 16730719 [PubMed - indexed for MEDLINE]

1: Fertil Steril. 2006 Jul;86(1):243-6. Epub 2006 May 30.

Tags: chromium picolinate, infertility, insulin resistance, obesity, trivalent chromium